These are the presentation slides from Session III of the 2025 MIRL Symposium, focusing on the Generalist Repository Ecosystem Initiative (GREI). This session provided attendees with practical resources and illustrative examples to support open data sharing and compliance with the NIH Data Management and Sharing (DMS) Policy. The presentation outlines the GREI Resource Toolkit for librarians and researchers, which includes: The Generalist Repository Comparison Chart The Generalist Repository Selection Flowchart Best Practices for Data Submission Checklist Guide for including generalist repositories in NIH DMS Plans Additionally, the slides feature real-world user stories from seven generalist repositories (Harvard Dataverse, Dryad, Figshare, Mendeley Data, OSF, Vivli, and Zenodo). These case studies demonstrate the tangible scientific benefits of data sharing, including data harmonization, enhanced reproducibility, support for multimodal datasets, and restricted access capabilities for sensitive health data.