Shukra is one among the Sapta Dhatus, that which present all over body and its main function is ‘Garbha Utpatti‘. Any abnormality leads to Shukravahasrotodusti and causes Nispraja, Garbha Vikruti, Aharshana and Klaibya.[1] All the Bruhatrayis explained about Astavidha Shukra Dusti, its Lakshanas and Doshic relation. Due to Aharaja, Viharaja, Manasika, Vaidyakrita and Abhigataja Nidanas, Dosha`s alone or in combine reaches Shukravaha Siras, there they affect Shukra quickly and results in Astavidhashukra Dusti acc to respective Doshas. In Charaka Samhita it is mentioned, Phenila Tanu Rooksha Vivarna Pooti Pichilam Anyadhatuupasamsrustam Avasadi as Astavidhashukra Dusti.[2] where in Sushruta Samhita and Astanga Hridaya it is mentioned as, Vata Pitta Sleshma Kunapagandi Granti Pootipuya Ksheena Mutrapureesharetas as Astavidha Shukra Dusti.[3] Oligospermia is reduced sperm count less than 15 million / ml of semen. Asthenospermia is reduced sperm motility less than 40% including progressive and non-progressive sperm. In today generation because of altered life style, unhealthy food, intoxications and stressful work people are more prone to suffer from abnormality of male reproductive system. Aim: The aim of study to know etiopathogenesis of Shukra Dusti and to assess oligo-asthenospermia in Shukra Dusti subjects. Methodology: This research utilized observational study. Data collection was conducted using case proforma. Results: Oligospermia and oligoasthenospermia were major findings in the subjects of Vataja Shukra Dusti. In Pittaja Shukra Dusti, asthenospermia was a major finding, followed by oligoasthenospermia. In Kaphaja Shukra Dusti, asthenospermia was a major finding.