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World Journal of Bio...arrow_drop_down
World Journal of Biology Pharmacy and Health Sciences
Article . 2025 . Peer-reviewed
Data sources: Crossref
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
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Premature greying of hair in children: A comprehensive review for pediatricians and primary care physicians

Authors: Venugopal, Reddy. I;

Premature greying of hair in children: A comprehensive review for pediatricians and primary care physicians

Abstract

Premature greying of hair (canities) in children is an increasingly recognized concern among parents and pediatricians. Although often benign, early hair depigmentation may be a clinical marker of nutritional deficiencies, autoimmune disorders, genetic predisposition, endocrine abnormalities, or oxidative stress related damage. The absence of standardized pediatrics guidelines leads to misdiagnosis, unnecessary anxiety, and missed opportunities for early intervention. This review synthesizes current evidence on epidemiology, pathophysiology, risk factors, diagnostic approach, and management of premature greying in children. A structured evaluation and targeted treatment of reversible causes especially vitamin B12, iron, vitamin D, zinc deficiency, and hypothyroidism can halt or partially reverse greying in many children. This article provides an evidence-based, clinically practical approach suitable for pediatricians, dermatologists, and general practitioners.

Keywords

Oxidative Stress, Micronutrient Deficiency, Trichology, Autoimmune Disorders, Thyroid Disorders, Vitamin B12 Deficiency, Pediatrics, Grey Hair in Children, Premature Canities

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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