This treatise presents the Non-Equilibrium Informational Field Theory (NIFT) Axioms, afoundational framework positing that the universe is fundamentally composed not of matter orenergy, but of physically real patterns of information evolving within a dissipative substrate. Weestablish a comprehensive set of axioms across three categories: Ontological, defining the informational pixel and the asymmetry principle as the origin of time; Dynamical, describingthe universe through telegraph causality and the informational coherence law; and Structural,explaining the emergence of spacetime geometry via holographic constraints and soliton closures. NIFT unifies the arrow of time, quantum mechanics, and gravity under a single coherentparadigm: that continuity is the macroscopic vote of a substrate too fine to be outvoted, and reality is the bridge between equilibrium and non-equilibrium states.