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ZENODO
Preprint . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Preprint . 2025
License: CC BY
Data sources: Datacite
ZENODO
Preprint . 2025
License: CC BY
Data sources: Datacite
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The NLRP2 inflammasome functions in a nuclear transcriptional network.

descriptionPublicationkeyboard_double_arrow_right Preprint 17 Nov 2025Publisher:Zenodo
Authors: Mamoor, Shahan;

doi: 10.5281/zenodo.17630743 , 10.5281/zenodo.17630744

The NLRP2 inflammasome functions in a nuclear transcriptional network.

Abstract

We recently described stage- and cell type-specific expression of NLRP2 in the human hematopoietic stem cell (HSC). We describe here a function of the NLRP2 innate immune sensor in a nuclear transcriptional network that involved the function of the RNA interference machinery (DROSHA), the DNA methyltransferase DNMT1, the non-coding RNA Xist and a molecule recently identified as regulating the activation or repression of Xist in response to induction DNA damage, MDC1.

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green