In furtherance of beliefs in the maxim which states that unity is power, the people of African descent in the late 18th century initiated a movement termed Pan-Africanism. The objective of the union was to have a formidable common front for the protection of African interest in the global arena, with larger expectations on collapsing all the vestiges of colonialism in Africa. Also, League of Nations was created in 1919 and was later substituted with United Nations in 1945 to ensure world peace and security. In consonance with liberal economic ideology, globalization continued to wax strong with the sole aim of relaxing all forms of protectionism in the world economy. However, the study observed contradictory stance of the two variables and set out to interrogate the Pan-Africanism and its relevance in the existing world order. We garnered the relevant information via documentary means from the secondary source and analyzed it with the Content Analysis. Theoretically, the study utilized the theory of Social Production and Reproduction of Material Value as a compass that elucidated the intricacies that necessitated the incessant struggle for status quo maintenance and change in the society. The theory maintained that man must produce to live, the production process is social in nature and that all the players in the production parlance are interested in satisfying their personal interest. Therefore, the study found out that in spite of the popularity of globalization, the Pan-Africanism is still relevant because it gives people of African descent an insurmountable protection in the global community. The study also suggested that African leaders should fortify their unity and oneness through maintenance of Pan-Africanism so as to have stake in the contemporary world order.