These uploaded datasets document the mean, maximum, and minimum estimates of near-surface temperature (T, in Kelvin), air pressure (p, in Pascal), specific humidity (SpH, unitless), and ambient PM2.5 concentration (in µgm-3) across the 21 global burden of disease (GBD)-defined global subregions for the baseline period (2005-14), and its projected estimates for mid-century (2041-50) and far-future (2071-80) under climate change scenarios.