Maritime strategy constitutes one of the most critical dimensions of the grand strategy of major powers. Although the prominence of this domain, initially underscored by Alfred Thayer Mahan in The Influence of Sea Power upon History, diminished with the evolution of global power structures, it has re-emerged as a central arena of geopolitical competition among great powers over the past two decades. The Indo-Pacific region, alongside the establishment of new security architectures such as the Quad and AUKUS, has become a pivotal locus in the strategic contest for global influence. Against this backdrop, this article examines the fundamental question: What role does the Indo-Pacific region occupy within the geopolitical equations of maritime powers, with particular emphasis on the Quad and AUKUS groupings? The findings of this descriptive-analytical inquiry reveal a progressive shift in the global economic and political center of gravity from the Atlantic to the Indo-Pacific. This transition, reinforced by emergent military and security coalitions, is expected to intensify rivalry and heighten tensions among leading maritime powers, particularly the United States and China.