Prehospital care (PHC) is a crucial stage in emergency management, providing immediate assistance before the patient arrives at the hospital. In Brazil, it is primarily organized through SAMU and SIATE, two services that, despite structural differences, share the goal of ensuring rapid, comprehensive, and humanized care. This study aimed to identify the challenges and potentialities of the multidisciplinary team's performance in PHC. A narrative review of scientific literature published between 2019 and 2024 was conducted. The selected studies address topics such as professional integration, quality of care, and operational barriers in emergency contexts. The findings were categorized into three main areas: team composition, encountered challenges, and observed best practices. Successful strategies identified include the adoption of clinical protocols, interprofessional training, use of digital technologies, and the promotion of humanized care. These practices enhance team cohesion and problem-solving capacity in critical settings. The study concludes that strengthening multidisciplinary work in PHC requires investment in public policies, continuous training, and support structures that ensure safe, ethical, and user-centered care.