The convergence of CRISPR gene-editing technology with quantum computing and artificial intelligence represents a paradigm shift in biomedical innovation. This interdisciplinary synthesis addresses current limitations in genomic analysis, off-target prediction, protein folding simulations, and gene therapy design through unprecedented computational power and modeling sophistication. As CRISPR transforms our ability to manipulate genetic material with precision, quantum AI offers solutions to overcome bottlenecks in speed, accuracy, and complexity management. This article explores the emerging synergies between these technologies, examining their potential to unlock breakthroughs in personalized medicine, disease eradication, biosecurity, and synthetic biology. Through comprehensive analysis of current capabilities, implementation challenges, and future directions, we present a roadmap for responsible innovation at the intersection of quantum computing, artificial intelligence, and genome editing.