This study aimed to show the importance and effects of physical therapy practice on patients who are diagnosed with COVID-19 disease, particularly how physical therapists perform their treatment sessions in the most effective way possible and how important these sessions are for patients with COVID-19 who need rehabilitation. In this study, researchers have used quantitative systematic review in analyzing the literature presented and have acquired 313 references from the data check yield. The researchers then screened and analyzed the titles and abstracts and the full texts resulting in a final selection of 13 references that were acquired using PRISMA and JBI evaluation methods. Based on the articles reviewed, physical therapy is effective in patients who are diagnosed with COVID-19. Physical therapists play a significant part during COVID-19 in providing respiratory support and active mobility to patients in hospitals, with early rehabilitation or with underlying difficulties that can be treated. Therefore, physical therapists had to go through a great deal of adjustments to comply with the new normal due to the pandemic.