This deliverable constitutes the initial Open Science and Data Management Plan (DMP) for the EIC Pathfinder Open project BioMembrOS. The main purpose of the DMP is to guide the implementation of the FAIR – Findable, Accessible, Interoperable, Re-usable – principles of the European Commission for data and other research outcomes. It specifies Data Governance and handling of data during the lifetime the project and beyond, lists the types of data are expected to be generated, whether and how it will be made open and accessible for verification and re-use, how it will be curated and preserved, and also addresses security issues. BioMembrOS is committed to openness according to the Horizon Europe principle "as open as possible, as closed as necessary".