
This narrative review compares low-calorie diet (LCD) and time-restricted eating (TRE) as dietary strategies for type 2 diabetes remission. It synthesizes evidence from clinical trials and emerging studies on physiological mechanisms, clinical outcomes, and real-world implementation, particularly in circadian-disrupted and underserved populations. The manuscript discusses intra-organ fat reduction, insulin sensitivity, circadian alignment, and adherence barriers, concluding that both LCD and TRE offer promise for personalized, equitable diabetes care. This version is adapted and expanded from an earlier manuscript submitted to Diabetes, Obesity, and Cardiometabolic Care (2025).
Shift Work Schedule/adverse effects, Diabetes Mellitus, Type 2, Low-calorie diet, Time-restricted eating, Adherence, Type 2 diabetes remission, Metabolic Health, Shift Work Schedule, Public Health, Lifestyle Intervention, Circadian Rhythm
Shift Work Schedule/adverse effects, Diabetes Mellitus, Type 2, Low-calorie diet, Time-restricted eating, Adherence, Type 2 diabetes remission, Metabolic Health, Shift Work Schedule, Public Health, Lifestyle Intervention, Circadian Rhythm
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