The study explores the clinical and epidemiological characteristics of chronic allergic respiratory diseases among children living in the ecologically unfavorable Aral Sea region. Chronic allergic diseases, particularly bronchial asthma, represent a major health burden in childhood worldwide, with an estimated 95.7 million cases in 2021. Environmental pollution factors such as contaminated air, soil, and water are believed to significantly contribute to the high prevalence of allergic respiratory conditions in this region. The research analyzes epidemiological indicators, including age, gender, place of residence, and exposure to environmental risk factors, as well as clinical symptoms such as cough, wheezing, dyspnea, and bronchial obstruction. Results indicate that urban residence, proximity to industrial zones, and exposure to tobacco smoke and poor living conditions increase the risk of allergic respiratory diseases. Boys are affected slightly more frequently than girls in early childhood, though prevalence tends to rise among older girls. The findings highlight the urgent need for preventive measures, early diagnosis, and effective treatment strategies for children living in environmentally burdened regions like the Aral Sea area.