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ZENODO
Article . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
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The Pharmacology of NSAIDs

descriptionPublicationkeyboard_double_arrow_right Article 23 Oct 2025Publisher:Zenodo
Authors: maria, murzaeva; Potnuri, Lohith;

doi: 10.5281/zenodo.17422789 , 10.5281/zenodo.17422790

The Pharmacology of NSAIDs

Abstract

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are one of the most widely used classes of medications globally.1 They are a cornerstone of treatment for pain, fever, and inflammation.2 This article provides a detailed overview of their pharmacology, including their mechanism of action, classification, pharmacokinetics, and the critical balance between their therapeutic effects and significant adverse effects.

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Keywords

pharmacology Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) mechanism of action cyclooxygenase (COX) COX-1 COX-2 prostaglandins thromboxane prostacyclin arachidonic acid analgesic anti-inflammatory antipyretic anti-platelet non-selective ibuprofen naproxen diclofenac selective COX-2 inhibitors coxibs celecoxib aspirin irreversible inhibition pharmacokinetics

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green