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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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Article . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
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A Rare Case of Bronze Diabetes Presenting as Diabetes Ketoacidosis

Authors: Kiran Shah; Akshay Kothari;

A Rare Case of Bronze Diabetes Presenting as Diabetes Ketoacidosis

Abstract

Abstract A decrease in the beta globulin chain, or thalassemia major, can lead to splenomegaly, extramedullary haematopoiesis, and severe anaemia. Iron overload occurs as a result of the mandatory blood transfusions required by thalassemia major patients to maintain acceptable erythrocyte levels. Secondary haemochromatosis, often known as bronze diabetes, is a fatal medical disease that may arise as a result of multiple blood transfusions. A 16-year-old male presented with complaints of polyuria, polydipsia and breathlessness in EMR. His random blood sugar was 564mg/dl, serum ketones were positive, arterial blood gas analysis showed high anion gap acidosis. His mother informed the patient was known case of thalassemia major since five years of age and was undergoing blood transfusions every 21 days along with chelation therapy. The patient was diagnosed to have diabetic ketoacidosis and was stabilized. Diffuse hyperpigmentation was evident on the sun-exposed areas of skin. Diagnosed as bronze diabetes the patient is on multiple doses of insulin and on chelation therapy

Keywords

Ferritin, Discoloration of Skin, Thalassemia Major, Diabetic Ketoacidosis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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