This research examined the influence of entrepreneurship education on self-esteem and conformity among adolescent secondary school students in the Calabar Education Zone of Cross River State. The research was guided by four research questions and four null hypotheses, tested at a 0.05 level of significance. An ex-post facto research design was adopted for the study. A structured questionnaire, developed by the researcher, served as the instrument for data collection. The sample consisted of 464 SS II students drawn from selected secondary schools in the zone. Data collected were analyzed using mean and standard deviation to answer the research questions, while independent t-test statistics were employed to test the null hypotheses.