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ZENODO
Article . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
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Impact of Subclinical Hypothyroidism in Pregnancy on Maternal and Fetal Outcomes: A Case-Control Study at a Tertiary Care Centre in Assam

Authors: Dr. Samarpita Sinha;

Impact of Subclinical Hypothyroidism in Pregnancy on Maternal and Fetal Outcomes: A Case-Control Study at a Tertiary Care Centre in Assam

Abstract

Background: Subclinical hypothyroidism (SCH), marked by elevated TSH with normal free T4, is increasingly recognized as a contributor to adverse pregnancy outcomes. This study investigates the maternal and fetal outcomes in pregnant women with SCH. Methods: This prospective case-control study included 120 pregnant women, divided into 60 SCH cases and 60 euthyroid controls. TSH and FT4 were measured trimester-wise. Outcomes including gestational complications, mode of delivery, and neonatal outcomes were recorded and analyzed. Results: SCH was significantly associated with higher rates of gestational hypertension (35%), anemia (13%), and oligohydramnios (17.5%). Neonatal complications such as low birth weight (30%), NICU admissions (17.5%), and IUGR (12.5%) were more prevalent in the SCH group. The difference in TSH levels between groups was statistically significant (p < 0.001). Conclusion: SCH in pregnancy is significantly associated with adverse maternal and fetal outcomes. Early screening and appropriate levothyroxine therapy may reduce these risks.

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green