The following two-part proof is centered on genuine personal control (GPC); often referred to as agent-causation/volition. Lemma 1 shows that GPC denial is self-refuting. Lemma 2 shows that physicalism/materialism necessitates GPC denial. Hence this overall proof shows that physicalism—is self-refuting. Doing so in a way that addresses all potential corresponding counters (e.g., quantum indeterminacy, compatibilism, emergentist/nonreductive physicalism, property dualism, epiphenomenalism, arguments from incredulity). Showing the acceptance of such counters to entail baselessly abandoning fundamental principles of logic and physics.