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ZENODO
Article . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
ZENODO
Article . 2025
License: CC BY
Data sources: Datacite
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NEW ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF UV -VISIBLE SPECTROSCOPY ANDUSING FTIR STUDY OF CHEMICAL STRUCTURE OF SULPIRIDE

Authors: Nandankumar K.*1, Kushala P., Harshitha A. S., Shankar Prasad D. B., Sanjay S.;

NEW ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF UV -VISIBLE SPECTROSCOPY ANDUSING FTIR STUDY OF CHEMICAL STRUCTURE OF SULPIRIDE

Abstract

Development and implementation of a simple, precise, and Accurate Zero order spectroscopic method for the estimation of Sulpiride in bulk and Tablet dosage form. The drug indicates the maximum absorption (λmax) at 212 nm in 0.2N HCl solutions and AUC in the absorption spectrum is measured in the wavelength range from 207 to 218 nm at a concentration range of 1-5µg/ml according to Beer’s law. Linearity analysis showed an R2 value of 0.998. The LOD & LOQ were found to be 0.0110 and 0.33 µg/ml. The %RSD was found less than 2%. The method has been validated according to Linearity, Precision, Accuracy, Robustness, Ruggedness, LOD and LOQ according to ICH guidelines. This method obeys the Beer’s law and met all the required specifications within the limit. FTIR analysis of Sulpiride active pharmaceutical ingredient gives different peaks of wavenumbers. FTIR data interpretation also gives information about purity and quality of sample and it also meets the required specifications.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green