Enterprises operating on Salesforce confront a persistent tension between agility and control. On one side, business teams expect rapid, low-code change through Flows, Process Builder legacy estates, and Apex services. On the other, security, privacy, and regulatory mandates require consistent enforcement of policies across a heterogeneous integration perimeter that spans first-party sales/service processes, partner and customer communities, analytics stacks, and external services invoked via platform events and APIs. This paper proposes an architectural approach to reconcile those demands: autonomous policy enforcement driven by AI-orchestrated workflows that observe user and system behavior, reason about policy context, and decide and act—closing the loop without human intervention for the vast majority of routine decisions while preserving human-in-the-loop governance for exceptional or high-risk cases. Building on the autonomic computing MAPE-K loop, policy-based management, attribute-based access control (ABAC), and complex event processing (CEP), the approach integrates Salesforce platform primitives—Flows, Apex, Platform Events, Shield Event Monitoring, Transaction Security, and Data Mask/Platform Encryption—into a cohesive, verifiable control plane. The paper contributes a reference architecture; a lifecycle for policy authoring, verification, simulation, and continuous learning; enforcement patterns for common CRM controls (access, data loss prevention, approvals, and session risk); and an evaluation methodology emphasizing correctness, latency, cost, and organizational adoption. While the work is framed around Salesforce, the principles generalize to policy orchestration in other SaaS ecosystems. The argument is grounded in pre-December 2023 literature on self-adaptive systems, run-time enforcement, ABAC, CEP, explainability, anomaly detection, and concept drift.