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From StrainRegistry to StrainInfo: tracking microbial strains through a FAIR deposition system

Authors: Schober, Isabel; Lissin, Artur; Witte, Julius F.; Lüken, Helko; Pukall, Rüdiger; Abt, Birte; Pester, Michael; +3 Authors

From StrainRegistry to StrainInfo: tracking microbial strains through a FAIR deposition system

Abstract

Poster presented at ECCO XLIII In scientific literature and databases, different strain identifiers can be used to describe the same microbialstrain, which significantly impedes the findability, reusability and integration of published information,and thus also the reproducibility of research results. In order to ensure the traceability of microbial strains,the StrainInfo database collects and matches all their known strain identifiers. To additionally improveand encourage the referencing and linking of microbial strain data, StrainInfo has introduced the DOI asa persistent identifier for strains. When researchers isolate and describe large sets of strains from microbiome studies they need persistentidentifiers early on to keep track of them throughout the deposition process in culture collections as wellas in publications and sequence submissions. The DSMZ has developed a bulk submission procedure forstrain collections that greatly simplifies the deposition of large sets of strains and provides StrainInfo DOIsearly in the process. This allows the tracking of the deposition statuses of strains and improves thetraceability by their DOI throughout literature and databases. A new deposition management system, called StrainRegistry, will further ease the process in the future.It will allow microbiologists to register strains, that they wish to deposit in a culture collection, with meta-and deposition data. This ensures that FAIR strain data is available from the outset. While the data willinitially be kept private, it will be possible to directly submit it to one or more participating culturecollections for deposition. Later, it can easily be integrated into StrainInfo and other databases.StrainRegistry will visualize the deposition status of each strain and facilitate communication between thedepositors and the responsible culture collection curators and thus assist researchers in managing thedeposition of strains.

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