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Article . 2025
License: CC BY NC ND
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Article . 2025
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Integrated Gene Expression Resource for Multi-Subtype Acute Myeloid Leukemia: A Global Reference Dataset

Authors: Rahi, Alireza;

Integrated Gene Expression Resource for Multi-Subtype Acute Myeloid Leukemia: A Global Reference Dataset

Abstract

Acute Myeloid Leukemia (AML) is a highly heterogeneous hematologic malignancy with multiple clinically relevant subtypes. Despite the availability of numerous gene expression datasets, there is no comprehensive, balanced, and multi-cohort resource integrating all major AML subtypes. Here, we present an integrated gene expression resource for seven key AML subtypes, curated from eight publicly available GEO datasets (GSE13159, GSE6891, GSE14468, GSE15434, GSE10358, GSE61804, GSE71014, GSE12417). The dataset comprises 338 samples with standardized metadata, consistent labeling, and batch-corrected expression matrices. Advanced preprocessing, label harmonization, and balanced sampling ensure equal representation across subtypes. This resource is ready for machine learning, biomarker discovery, and cross-study validation, providing a global reference dataset for AML research.

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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