Cloud adoption speedup requires businesses to make DevOps practices secure and cost-effective and compliant across all operations. This article provides an all-inclusive framework which establishes Secure and Cost-Optimized DevOps deployment in the Cloud while monitoring automation together with regulatory compliance and cost optimization. The analysis investigates the combination of security controls with CI/CD pipelines through DevSecOps and uses Infrastructure as Code (IaC) for standardized cloud deployments and includes third-party and cloud-native tools for policy enforcement and cost management. The article presents DevOps decision making best practices for agile governance balance by analyzing real-world implementation case studies and performance metrics through a mixed research approach. The framework develops threat detection systems beforehand while using AWS CloudWatch alongside Azure Monitor and GCP Operations Suite for scaling monitoring capabilities for businesses to achieve cost optimization by implementing smart resource allocation methods which reduce waste. Research findings expand the existing knowledge that helps DevOps teams and cloud architects merge their work with compliance officers to create robust software delivery solutions in elastic cloud infrastructure systems.