ABSTRACT:A gradual increase in the overall temperature of the earth’s atmosphere generally attributed to the greenhouse effect caused by increased levels of carbon dioxide chlorofluorocarbon [CFC] and other pollutants.pre- test post- test research design used to observe the effectiveness of self -instructional module among high school students regarding Global Warming and its impact on health. This study was conducted in Govt. Girls Higher Secondary School, Panagar. The sample size of this study consists of 60 students. Self-structured questionnaire is used to assess the knowledge level of the students. knowledge. 23(38%) of students have poor knowledge. None of the students have good knowledge. A pre-experimental approach was adopted. Sample size 60 high school students. It depicted that mean posttest knowledge score 22.17 was apparently higher than mean pretest knowledge score 11.67. This indicates that self-instructional module was effective and increased knowledge score of high school students regarding Global Warming and its impact on health. The study finding showed a highly significant difference (t=12.7, p-0.05] between pretest knowledge score 11.67 and posttest knowledge score 22.17