This document is the policy brief (extended summary) of the roadmap for the Virtual Human Twin, containing the main elements in terms of context, vision, building blocks, and recommendations for the realization of the VHT. The VHT roadmap is a deliverable of the EDITH project. EDITH, “Ecosystem for digital twins in healthcare”, was a coordination and support action funded by the Digital Europe program (grant number 101083771) that brought together the entire ecosystem working on activities related to the Virtual Human Twin in the broadest sense. The policy brief is available in English, French, German, Italian, Spanish, Polish and Swedish. The full version of the roadmap is available at: http://doi.org/10.5281/zenodo.14769224 after final approval.Further information on the EU Virtual Human Twin Initiative is available on the website of the European Commission: https://digital-strategy.ec.europa.eu/en/policies/virtual-human-twins.