Sea cucumbers are marine invertebrates, found in deep seas across the world. They have high commercial value as they are considered as a luxury food item and used in traditional medication due to their impressive nutritional profile and curative effects. Sea cucumber contain a wide range of bioactive compounds namely Triterpene glucosides, bioactive peptides, fatty acids, Chondroitin sulfates, lectins which exhibits therapeutic activities including antiangiogenic, anticancer, anticoagulant, antitumour, antiviral, antifatigue, antioxidant, wound healing have been ascribed to various species of sea cucumber. In this review we have presented a general view on major health benefits of sea cucumber.