The research work was carried out using gas chromatography to determine the nutritional status in Crab and Periwinkle from Bayelsa State. Base on the analysis the following results were obtained. Protein in crab 19.84% vitamin 10.064% fatty acid 100 and very high percentage of mineral while Periwinkle has protein of 22.95% fatty acid of 100% and vitamin of 6.37% and very high percentage of mineral. In conclusion, from the studies, it was observed that, despite oil exploitation activities in Bayelsa which may predispose it to pollution, crab and periwinkle from the study still contain high nutritional value Protein is an important macronutrient that every cell in the body needs. It helps build and repair cells and body tissues, including the skin, hair, muscle, and bone Polyunsaturated fatty acids (PUFAs) are fatty acids that contain more than one double bond in their backbone. This class includes many important compounds, such as essential fatty acids and those that give drying oils their characteristic property.