Dirofilaria infections constitute an uncommon clinical entity in humans. The most common Dirofilaria species affecting the humans include D. repens and D. immitis . There are about 40 other species of Dirofilaria known to cause diseases in humans.The incidence of these infections have been on a rise with more cases being reported from different parts of the world each year.More than 1000 cases have been cited in literature now in diverse geographical locations and is still rising. European countries surrounding the Mediterranean region have been noted to be amongst the most affected areas. The key to diagnosis is differentiating it from other pathologies with similar presentations like malignant neoplasms ,sebaceous cysts ,fungal infections and abscesses. This article reports a case series of the clinical presentation, characteristics and treatment of human dilofilariasis over the past the past 2 years at our institute.