Research is the backbone of human civilization and industrial revolution all over world. Academics is playing a very important role in identifying human and industrial needs and satisfying them by producing desired goods and services through research and innovation. During 2017 to 2022 researches out has increased to 54% whereas research papers have risen to 1.3mn[1]. Currently India ranks. Artificial intelligence is a newly developed domain of knowledge which will affect Indian academics and research positively and negatively. With the rapid integration of AI-driven tools, machine learning algorithms, and big data analytics, Indian academic institutions are experiencing transformative changes in research methodologies, knowledge dissemination, and innovation. Use of AI tools will increase accuracy of result predictions, data analysis, and reshaping traditional pedagogies, fostering interdisciplinary collaboration, and accelerating scientific breakthroughs. However, infrastructural bottle necks, data security and ethical issues have hampered used of AI in Indian academics. This paper explores the existing role, applications, benefits, and challenges of AI in Indian academic research and innovation.