This document focuses on the integration of digital twins in data spaces: it provides a context on data spaces, digital twins, IoT and edge computing and standardisation: it provides an analysis on the integration of digital twins in data spaces taking an architectureapproach; it describes a large number of digital twin use cases in domains such as agriculture, connectedvehicles, smart cities, energy, smart manufacturing; The document can be used to provide insights and sources for future standardisation work related tothe integration of digital twins in data spaces.This document also leverages the following reports: The EU Observatory for ICT Standardisation (EUOS) published in June 2022 a report prepared bythe StandICT task work group (TWG) entitled Landscape of Digital Twins. AIOTI published in September 2022 a report prepared by the standardisation working group (WG)entitled Guidance for the Integration of IoT and Edge Computing in Data Spaces. BDVA published in February 2024 a report prepared by the task force on data spaces and taskforce on standards entitled Data Sharing Spaces and Interoperability.