We present an approach which makes use of the twiness between SNe Ia at low z and in the Hubble flow to determine the value of H0. The method has been first tried in SNe Ia at middle distances up to 40 Mpc in order to compare the results with other methods. It has shown that the twin pairing can reduce the error in relative distance moduli to 0.04 mag. We have applied now the method to SNe Ia twins in he Hubble flow. We find that the Hubble tension is real. We obtain (preliminar) H0 at 71 $\pm$1.5 km $^{-1}$ Mpc$^{-1}$. We have examined as well the isotropy of H0 along different directions in sky. Whereas in Pantheon+ we find some anisotropy at low confidence level, we find isotropy in other large SNe Ia cosmological samples.