Crude drug obtained from different natural source are used in treatment of wide spectrum of disease. Most of the crude drug are obtained from plant and only a small number come from animal and minerals origin.Drug obtained from plant consists of entire plant or their parts. Alstonia Scholaris is native to South -East Asian Countries and the Indian Subcontinent. In India,the plant is found all over the sub - Himalayan region.especially east of the Yamuna river.The genus Alstonia comprises about 60 species throughoutthe world and about 6 species occur in India. Amongst them,Alstonia scholaris, Alstonia macrophylla and Alstonia venenata R. Br.have medicinal importance .It possoses wide range of phytochemicals showing various pharmacological activities such as astringent, antimicrobial, antimalarial, diarrhoea and dysentery, improve immune power,anticancer.Material and Methods:-Literature about Alstonia Scholaris was collected by using electronic and library search.Result:- In this article we discuss and summaries compressive data about uses, phytochemistry,and pharmacology.