This article provides a comprehensive analysis of the derivational mechanisms and hypocoristic (affectionate or diminutive) name formation processes within national anthroponymic systems. It delves into the structural, phonological, and cultural factors that shape how proper names are modified or adapted to reflect familiarity, affection, or informality. Drawing on examples from Uzbek, Russian, and English, the paper investigates both universal patterns and culturally specific practices in forming derivative and affectionate name variants. The study reveals that name derivation not only serves linguistic convenience but also mirrors deep sociocultural values related to identity, interpersonal relationships, and historical traditions. It highlights the importance of studying naming practices to understand broader linguistic and cultural systems.