Abstract: Postpartum blues, colloquially termed “baby blues,” affect a substantial number of women within the first two weeks following childbirth. Although the condition is self-limiting and transient in most cases, it can significantly affect a mother's emotional health and her ability to bond with the newborn. When unaddressed, it may progress to more severe mental health issues such as postpartum depression or anxiety. Nurses play a pivotal role in the early recognition and management of postpartum emotional distress, as they often maintain close contact with new mothers during this critical period. This review explores the clinical features, etiological factors, screening strategies, and evidence-based nursing interventions for managing postpartum blues. Emphasis is placed on the importance of psychosocial support, family involvement, antenatal education, and timely referrals. By adopting a compassionate and holistic approach, nurses can help ensure optimal maternal mental health during the postpartum transition.