Depersonalization-derealization disorder (DPDR) is a complex cognitive state characterized by a persistent sense of detachment from oneself or the external world. While commonly associated with anxiety and dissociation, traditional treatment methods often fail to address its self-sustaining nature. This study introduces a new model of DPDR based on cognitive inertia — a mechanism in which attentional fixation and perceptual rigidity prevent the system from returning to flexible, natural perception. The research explores: neurophysiological mechanisms behind DPDR, the role of attentional loops and interpretation coupling, and methods of recovery through awareness-based practices, sensory stimulation, and physical engagement. A comparative analysis is also provided, distinguishing DPDR from generalized anxiety disorders and depression, with a focus on unique mechanisms of perceptual fixation. Included in this publication:Alongside the core scientific manuscript, we attach an additional document titled: > “Not Danger, but a Knot: How Anxiety Turns into DPDR — and How to Untie It” This companion text presents the model in a clear, structured, human-readable format, designed to help affected individuals recognize the fixation loop and apply recovery strategies in real life. It is suitable for both clinicians and the broader public interested in consciousness, anxiety, and cognitive feedback mechanisms. --- For further exploration of this work and related tools, visit: dpdr-help.com