This record contains the datasets used in “Growth history leaves a geometric trace in puzzle cells”. The datasets are organized into the following tar.gz files: Contours.tar.gzCell contour data from various plant species used for analysis of puzzle cell shapes. Drug treatments.tar.gzDescription: Data from pharmacological treatments of Arabidopsis thaliana cotyledons with oryzalin and latrunculin B. LGO mutant analysis.tar.gzEpidermal cell data from leaves of mutants for LOSS OF GIANT CELLS FROM ORGANS (LGO) in Arabidopsis thaliana. Maize data.tar.gzData from time-lapse experiments on leaf epidermis of maize (Zea mays) using the sequential replica method. Miocene species analysis.tar.gzEpidermal cell data from Miocene plant fossils used for analysis of puzzle cell shapes in early plant species. Models.tar.gzModel files, simulation data and parameter files. The file also includes two deb packages of the MorphoDynamX software for Ubuntu 22: MorphoDynamX_CUDA11_Ubuntu22.deb compiled with CUDA 11 support for systems with compatible NVIDIA graphics cards; MorphoDynamX_OMP_Ubuntu22.deb compiled with OpenMP support for systems without NVIDIA graphics cards or for running simulations on CPU only. MT data and mass spring model.tar.gzData on microtubule orientation in epidermal pavement cells and files related to the mass-spring mechanical model simulations. Mutants.tar.gzEpidermal cell data from Arabidopsis thaliana mutants with defects in puzzle cell shape formation (i.e., CA-ROP2, any1, ctr1). Please extract the relevant tar.gz file(s) to access the datasets. For any questions or further information about the datasets, please contact the corresponding authors:Mateusz Majda (Mateusz.Majda@unil.ch) or Richard S. Smith (Richard.Smith@jic.ac.uk) Please cite the related publication when using these datasets.