Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Other literature type . 2025
License: CC BY
Data sources: ZENODO
ZENODO
Conference object . 2025
License: CC BY
Data sources: Datacite
ZENODO
Conference object . 2025
License: CC BY
Data sources: Datacite
versions View all 2 versions
addClaim

Seizure Propagation Maps in Patients with Refractory Epilepsy

Authors: Zoé Bolluijt; Emma Depuydt; Serge Vulliémoz; Pieter van Mierlo;

Seizure Propagation Maps in Patients with Refractory Epilepsy

Abstract

Epilepsy impacts approximately 50 million people worldwide, yet pharmacological treatment fails to achieve seizure freedom in one-third of patients, resulting in drug-resistant epilepsy. The most effective treatment to render refractory epilepsy patients seizure-free is surgical resection of the seizure onset zone. Nevertheless, only around 55% of patients become seizure-free after epilepsy surgery. Eligibility for surgery is assessed through various tests, including long-term electroencephalography (EEG), to localize the seizure onset zone and track the spread of seizure activity. Using Dynamical Imaging of Coherent Sources (DICS), a technique that traces the origin of oscillatory brain activity based on the seizure EEG data, the seizure propagation over time can be mapped in the brain. These propagation maps provide insights into patient-specific seizure dynamics, highlighting how seizure spread may vary across subjects, seizures, and frequency bands. In this study, we developed the pipeline to map the seizure propagation and tested it using multiple seizures. In the future, we want to validate these propagation maps based on intracranial records and seizure semiology. Furthermore, we want to identify biomarkers for predicting post-surgical seizure freedom based on these propagation patterns.

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green