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ZENODO
Report . 2025
Data sources: ZENODO
ZENODO
Report . 2025
Data sources: Datacite
ZENODO
Report . 2025
Data sources: Datacite
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Scientific Review on PerioCream and NitrAdine: From Microbiota Modulation to Clinical Efficacy in Periodontal Therapy

descriptionPublicationkeyboard_double_arrow_right Report 19 Mar 2025 English Publisher:European Institute of Medical Studies (EIMS) H.E.I.
Authors: Mascolo, Andrea;

doi: 10.5281/zenodo.15049809 , 10.5281/zenodo.15049808

Scientific Review on PerioCream and NitrAdine: From Microbiota Modulation to Clinical Efficacy in Periodontal Therapy

Abstract

This scientific review explores the microbiological, clinical, and therapeutic potential of PerioCream, a NitrAdine-based mucoadhesive periodontal paste. PerioCream is designed as an adjunct to Scaling and Root Planing (SRP) to enhance healing, reduce microbial recolonization, and improve patient-reported outcomes. The study provides a comprehensive analysis of previous research, highlighting:📌 The antimicrobial and bioadhesive properties of NitrAdine formulations.📌 Comparative efficacy of PerioCream versus chlorhexidine (CHX), photodynamic therapy (aPDT), and probiotic-based adjuncts.📌 Rationale for the 2025 clinical investigation, assessing real-world effectiveness using HRQL (Health-Related Quality of Life) and VAS (Visual Analogue Scale) assessments. This review serves as a scientific foundation for the upcoming clinical study, contributing to the growing body of evidence on non-antibiotic periodontal therapies. 🔗 For more research and updates, visit the NitrAdine & PerioCream Research Hub.

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Keywords

periodontology, Wound Healing, scaling and root planing, FOS: Clinical medicine, Periodontal therapy, biofilm control, antimicrobical, Microbiology, mucoadhesive, antimicrobial agent, Dentistry, FOS: Biological sciences, VAS, NitrAdine, Periodontitis, Periocream, HQRL

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average