Abstract: Infection control in hospital settings is a critical component of healthcare delivery, aimed at preventing and mitigating healthcare-associated infections (HAIs). This review article explores various infection control practices, including hand hygiene, personal protective equipment (PPE), sterilization and disinfection, isolation protocols, and environmental hygiene. The article also discusses the role of healthcare workers in infection prevention, challenges in maintaining infection control, and the impact of emerging infectious diseases on hospital settings. Recommendations for enhancing infection control strategies in healthcare institutions are also presented.