
BRAINscape: A Comprehensive Multi-Omics Analysis Tool Overview BRAINscape is an R package designed for integrative multi-omics analysis, specifically developed for the MU-BRAIN dataset, a multiethnic RNAseq dataset. The package facilitates stratified eQTL mapping and Differential Expression Analysis, providing a user-friendly framework for researchers to explore genetic and transcriptomic associations. Features - eQTL Analysis: Supports cis and trans eQTL mapping.- Differential Expression Analysis: Uses DESeq2 for robust transcriptomic profiling.- Interactive Data Exploration: Shiny-based web interface for data visualization.- Supports Ethnicity-Specific Analysis: Users can filter results by Hispanic and Non-Hispanic Whites (NHW) groups.- Advanced Visualization: - Manhattan Plots for eQTL results. - Volcano Plots for Differential Expression Analysis.
Genetic Variation/genetics, MU-BRAIN, Alzheimer, GWAS, DESeq2, eQTL
Genetic Variation/genetics, MU-BRAIN, Alzheimer, GWAS, DESeq2, eQTL
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