This document is the deliverable “D2.1 – Analysis of operative and technological context” of the HorizonEurope project “eCREAM enabling Clinical Research in Emergency and Acute care Medicine throughautomated data extraction” (hereinafter also referred to as “eCREAM”, project number: 101057726).This document outlines the necessary elements to set up the data extraction module, which is a goal of WorkPackage 2, and includes information on the purpose of this activity, as well as the stakeholders involved.Details are provided on what needs to be done in order to successfully complete the task.