Statistics and Probability is a foundational discipline that equips learners with critical analytical and decision-making skills, essential for understanding and addressing real-world challenges in various academic and professional contexts. This study assessed the effectiveness of video-based instruction in enhancing the academic performance of Grade 11 learners in Statistics and Probability at Hinlayagan National High School, Trinidad II District, Bohol Division, during the academic year 2020-2021. The investigation aimed to explore learners' academic performance before and after implementing video-based instruction and determine whether the intervention resulted in a statistically significant improvement. This study was conducted in response to the identified challenge of low academic performance in Statistics and Probability. To address this issue, video-based instruction was introduced as a supplementary tool to the existing modular print-based instruction employed by the school. A pre-test–post-test research design was employed to collect and analyze data, focusing on the academic performance of learners during the third and fourth quarters in Statistics and Probability. Data collection utilized division-developed summative tests and performance tasks, which underwent rigorous statistical analysis to ensure the validity and reliability of the findings. Findings revealed a significant improvement in the learners' academic performance following the implementation of video-based instruction. Statistical analysis demonstrated a substantial increase in the number of learners achieving higher performance levels. The proportion of learners classified as performing at a satisfactory level increased, and notable improvements were observed in the very satisfactory and outstanding performance categories. Overall, a significant number of learners advanced by at least one performance level, highlighting the positive impact of video-based instruction on academic achievement. These results give emphasis to the potential of video-based instructional materials as an effective pedagogical tool to enhance learning outcomes in Statistics and Probability, particularly in contexts where modular print-based instruction is the primary mode of delivery.