Botulinum toxin is a versatile therapeutic agent that has become the most successful non-surgical method in Brazil for being effective in various dental treatments. The main purpose of this study is the therapeutic use of botulinum toxin in Dentistry. In order to satisfy the objectives of this study, a literature review was held. It is known that the dentist has extensive knowledge of the anatomy of head and neck, so he is highly skilled to treat pathologies regarding this part of the oral cavity and face with the botulinum toxin since he possesses specific training and knowledge about its use. If executed by a skilled professional, we can expect to obtain safe and conservative results, providing comfort to the patient.