This report provides an update to the initial version of the ELIXIR-STEERS Project Handbook, shown in Deliverable D1.1 . The project handbook follows the Open PM2 best practices to provide the board members and the project participants with a clear definition of their roles and responsibilities as well as the releva processes and assets the project will use to ensure contractual commitments in the Grant Agreement are delivered on time and within the scope and budget and with the expected level of quality