This paper examines the impact of Maersk’s adoption of cloud-based blockchain technology integrated with machine learning (ML) in optimizing logistics and supply chain management. As one of the largest players in the global logistics market, Maersk leverages the combination of blockchain and ML to enable secure and fully automated transactions. These technologies not only enhance business efficiency but also streamline international goods flow and ensure transparency throughout the supply chain. The paper analyzes the innovations implemented by Maersk, highlighting how this integration contributes to the company’s competitive edge in the global logistics sector by improving operational and economic outcomes.