Synthesis of Carbazole-1&3-Acids by using Suzuki Coupling followed by Cadagon Reductive Cyclization
Synthesis of Carbazole-1&3-Acids by using Suzuki Coupling followed by Cadagon Reductive Cyclization
Using a Suzuki coupling followed by Cadagon reductive cyclization as a key steps, the first synthesis of 1-carboxylic acid carbazole has been achieved in 4 steps and in 65% overall yield. In the present work, this approach was applied to the total synthesis of carbazole alkaloids. This is the simple way to synthesise 9H-Carbazole-1-carboxylic acid and 9H-Carbazole-2-carboxylic acid.
Miyaura coupling, Bispinacolatodiboron, TetrakisdiphenylphosphinoPd catalyst, Triphenyl phosphine, Cadagon reductive cyclization., Miyaura coupling, Bispinacolatodiboron, TetrakisdiphenylphosphinoPd catalyst, Triphenyl phosphine, Cadagon reductive cyclization
Miyaura coupling, Bispinacolatodiboron, TetrakisdiphenylphosphinoPd catalyst, Triphenyl phosphine, Cadagon reductive cyclization., Miyaura coupling, Bispinacolatodiboron, TetrakisdiphenylphosphinoPd catalyst, Triphenyl phosphine, Cadagon reductive cyclization
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!