Synthesis of substituted pyrazoles derivatives was undertaken employing a convenient and easily accessible procedure. In this article some 4, 5- dihydro- 3, 5- diaryl- N- [(anylamidolimido) alkyl] pyrazole- 1- carbothrioamides/carboxamides were synthesized from 1, 3- diaryl- prop- 2- enes as starting material for their characterization and antimicrobial activity involving five fungal and four bacterial strain in vitro. Synthesized substituted pyrazole compounds were obtained in the yields varying 53-68%.