The study adopted explanatory research, research strategy used was cross-sectional survey, population of the study were Denkyira Ayanfuri Gyamanhene and his sub chiefs and elders of Denkyira Ayanfuri Gyaman. Source of data collection was primary source, method of data collection was interview ; objectives of the study were achieved through research. Background of the study was brief introduction to the history of Denkyira Ayanfuri Gyaman. With the literature review, study considered the views of Denkyira Traditional Leaders about Denkyira Ayanfuri Gyaman. Problem statement of the study was " Significance of Denkyira Ayanfuri Gyaman Stool in Central Region of Ghana". The study found out that the ancestors of Denkyira Ayanfuri Gyaman were Denkyiras who migrated from Denkyira Abankeseso, main divisions of Denkyira Kingdom were Gyaasedom, Adontedom Akwamantire and Kyerefem, AKwamuhene could act as a Paramount Chief, ancestors of Denkyira Ayanfuri Gyaman controlled Denkyira AKwamu Division of Denkyira Kingdom, ancestors of Denkyira Ayanfuri Gyaman departed from Denkyira Gyaman Dadaa during the reign of Nana Boa Agyaako I and Nana Yaw Asem Bediako I gave Denkyira Dunkwahene land to settle on. Ancestors of Denkyira Ayanfuri Gyaman were involved in the battle of Feyiase, early ancient chiefs who died on Denkyira Ayanfuri Gyaman Stool, Nana Anofi Gyeabour II occupied Denkyira Ayanfuri Gyaman Stool for three consecutive times, Denkyira Ayanfuri Gyamanhene used ponponsuo Akofena to swear oath of allegiance to his people ; Denkyira Ayanfuri Gyamanhene Stool was made by Nana Boa Agyaako I. Okomfo Yaa Dodo was Denkyira AKwamu Fetish Priestess, spiritual powers of Denkyira AKwamu Division of Denkyira Kingdom dwelled at Denkyira Ayanfuri Gyaman, Denkyira Ayanfuri Gyaman Stool's sons were senior officers in Denkyira Adum Division of Kingdom, Denkyira Akrofuom land belonged to Denkyira Ayanfuri Gyamanhene and Ekuona Family occupied Denkyira Ayanfuri Gyaman Stool. The families at Ahafo Mbehame and Denkyira Jukwa Mfuom could occupied Denkyira Ayanfuri Gyaman Stool, Denkyira Ayanfuri Gyaman royal, Nana Kwadwo Poku was enstooled as Kyidomhene of Denkyira Jukwa Mfuom, Nana Bronii and Nana Kofi Mensah were kyeamehene at Denkyira Jukwa Mfuom. Denkyira Ayanfuri Gyamanhene, Nana Kwadwo Nuamah sold his birth right at Denkyira Dunkwa Atechem, Nana Kwadwo Tom was Denkyira AKwamu Adontehene, Denkyira Ayanfuri Gyamanhene's position as Denkyira AKwamuhene was historic and Denkyira Ayanfurihene was promoted to Denkyira AKwamuhene through deception. Nana Anofi Gyeabour II family was the dominant family at Denkyira Ayanfuri Gyaman.