Background: Effective root canal cleaning is vital for the success of endodontic therapy. Traditional syringe irrigation often fails to adequately clean complex root canal anatomies, particularly in the apical third, necessitating the development of advanced irrigation techniques. Ultrasonic, laser-activated, and mechanically assisted irrigation systems aim to enhance the removal of debris and smear layers, improving treatment outcomes. Aim: This study aimed to compare the efficacy of traditional syringe irrigation, ultrasonic irrigation, laser-activated irrigation, and mechanically-assisted irrigation in removing debris and smear layers from root canals. Methods: Sixty extracted single-rooted teeth were randomly divided into four groups (n=15 per group), each subjected to one of the irrigation techniques. Root canals were prepared using a standardized protocol and evaluated for cleanliness in the coronal, middle, and apical thirds using scanning electron microscopy (SEM). Data were analyzed using one-way ANOVA and Tukey’s post hoc tests, with significance set at p < 0.05. Results: Laser-activated irrigation achieved the highest cleaning efficacy, with mean scores of 2.0 ± 0.3 for debris and 2.2 ± 0.3 for smear layers. Mechanically-assisted irrigation also performed well (debris: 2.3 ± 0.4; smear layers: 2.5 ± 0.4). Ultrasonic irrigation showed moderate effectiveness, while traditional syringe irrigation was the least effective (debris: 4.1 ± 0.5; smear layers: 4.2 ± 0.4). Statistical analysis revealed significant differences among the groups (p < 0.05). Conclusion: Laser-activated irrigation proved to be the most effective technique for root canal cleaning, followed by mechanically-assisted irrigation. Ultrasonic irrigation demonstrated moderate performance, while traditional syringe irrigation showed limited efficacy, particularly in the apical third. Recommendations: The study highlights the need to incorporate advanced irrigation techniques such as laser-activated and mechanically-assisted systems for better clinical outcomes. Future clinical trials are recommended to validate these findings and assess their long-term impact.

Background: Effective root canal cleaning is vital for the success of endodontic therapy. Traditional syringe irrigation often fails to adequately clean complex root canal anatomies, particularly in the apical third, necessitating the development of advanced irrigation techniques. Ultrasonic, laser-activated, and mechanically assisted irrigation systems aim to enhance the removal of debris and smear layers, improving treatment outcomes. Aim: This study aimed to compare the efficacy of traditional syringe irrigation, ultrasonic irrigation, laser-activated irrigation, and mechanically-assisted irrigation in removing debris and smear layers from root canals. Methods: Sixty extracted single-rooted teeth were randomly divided into four groups (n=15 per group), each subjected to one of the irrigation techniques. Root canals were prepared using a standardized protocol and evaluated for cleanliness in the coronal, middle, and apical thirds using scanning electron microscopy (SEM). Data were analyzed using one-way ANOVA and Tukey’s post hoc tests, with significance set at p < 0.05. Results: Laser-activated irrigation achieved the highest cleaning efficacy, with mean scores of 2.0 ± 0.3 for debris and 2.2 ± 0.3 for smear layers. Mechanically-assisted irrigation also performed well (debris: 2.3 ± 0.4; smear layers: 2.5 ± 0.4). Ultrasonic irrigation showed moderate effectiveness, while traditional syringe irrigation was the least effective (debris: 4.1 ± 0.5; smear layers: 4.2 ± 0.4). Statistical analysis revealed significant differences among the groups (p < 0.05). Conclusion: Laser-activated irrigation proved to be the most effective technique for root canal cleaning, followed by mechanically-assisted irrigation. Ultrasonic irrigation demonstrated moderate performance, while traditional syringe irrigation showed limited efficacy, particularly in the apical third. Recommendations: The study highlights the need to incorporate advanced irrigation techniques such as laser-activated and mechanically-assisted systems for better clinical outcomes. Future clinical trials are recommended to validate these findings and assess their long-term impact.